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Duplex signaling by CaM and Stac3 enhances Ca(V)1.1 function and provides insights into congenital myopathy

Ca(V)1.1 is essential for skeletal muscle excitation–contraction coupling. Its functional expression is tuned by numerous regulatory proteins, yet underlying modulatory mechanisms remain ambiguous as Ca(V)1.1 fails to function in heterologous systems. In this study, by dissecting channel trafficking...

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Detalles Bibliográficos
Autores principales:	Niu, Jacqueline, Yang, Wanjun, Yue, David T., Inoue, Takanari, Ben-Johny, Manu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080896/ https://www.ncbi.nlm.nih.gov/pubmed/29950399 http://dx.doi.org/10.1085/jgp.201812005

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