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IgA—about the unexpected

In this issue of JEM, Nakajima et al. (https://doi.org/10.1084/jem.20180427) demonstrate that glycan-dependent, epitope-independent IgA coating of intestinal bacteria alters bacterial gene expression and metabolism. This conferred coated bacteria with fitness within the mucus niche and contributed t...

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Detalles Bibliográficos
Autores principales: Macpherson, Andrew J., Ganal-Vonarburg, Stephanie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080912/
https://www.ncbi.nlm.nih.gov/pubmed/30045944
http://dx.doi.org/10.1084/jem.20181153
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author Macpherson, Andrew J.
Ganal-Vonarburg, Stephanie C.
author_facet Macpherson, Andrew J.
Ganal-Vonarburg, Stephanie C.
author_sort Macpherson, Andrew J.
collection PubMed
description In this issue of JEM, Nakajima et al. (https://doi.org/10.1084/jem.20180427) demonstrate that glycan-dependent, epitope-independent IgA coating of intestinal bacteria alters bacterial gene expression and metabolism. This conferred coated bacteria with fitness within the mucus niche and contributed to intestinal homeostasis through cross-phylum interactions.
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spelling pubmed-60809122019-02-06 IgA—about the unexpected Macpherson, Andrew J. Ganal-Vonarburg, Stephanie C. J Exp Med News In this issue of JEM, Nakajima et al. (https://doi.org/10.1084/jem.20180427) demonstrate that glycan-dependent, epitope-independent IgA coating of intestinal bacteria alters bacterial gene expression and metabolism. This conferred coated bacteria with fitness within the mucus niche and contributed to intestinal homeostasis through cross-phylum interactions. Rockefeller University Press 2018-08-06 /pmc/articles/PMC6080912/ /pubmed/30045944 http://dx.doi.org/10.1084/jem.20181153 Text en © 2018 Macpherson and Ganal-Vonarburg http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle News
Macpherson, Andrew J.
Ganal-Vonarburg, Stephanie C.
IgA—about the unexpected
title IgA—about the unexpected
title_full IgA—about the unexpected
title_fullStr IgA—about the unexpected
title_full_unstemmed IgA—about the unexpected
title_short IgA—about the unexpected
title_sort iga—about the unexpected
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080912/
https://www.ncbi.nlm.nih.gov/pubmed/30045944
http://dx.doi.org/10.1084/jem.20181153
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