Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities

The mammary epithelium depends on specific lineages and their stem and progenitor function to accommodate hormone-triggered physiological demands in the adult female. Perturbations of these lineages underpin breast cancer risk, yet our understanding of normal mammary cell composition is incomplete....

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Detalles Bibliográficos
Autores principales: Casey, Alison E., Sinha, Ankit, Singhania, Rajat, Livingstone, Julie, Waterhouse, Paul, Tharmapalan, Pirashaanthy, Cruickshank, Jennifer, Shehata, Mona, Drysdale, Erik, Fang, Hui, Kim, Hyeyeon, Isserlin, Ruth, Bailey, Swneke, Medina, Tiago, Deblois, Genevieve, Shiah, Yu-Jia, Barsyte-Lovejoy, Dalia, Hofer, Stefan, Bader, Gary, Lupien, Mathieu, Arrowsmith, Cheryl, Knapp, Stefan, De Carvalho, Daniel, Berman, Hal, Boutros, Paul C., Kislinger, Thomas, Khokha, Rama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080920/
https://www.ncbi.nlm.nih.gov/pubmed/29921600
http://dx.doi.org/10.1083/jcb.201804042

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