Sorting the trash: Micronucleophagy gets selective

During micronucleophagy, the nucleolus is targeted by autophagic degradation, but although nucleolar proteins are recycled, ribosomal DNA is spared. Mostofa et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201706164) reveal that the separation of these two nucleolar components is mediated by...

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Detalles Bibliográficos
Autores principales: Verlhac, Pauline, Reggiori, Fulvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080933/
https://www.ncbi.nlm.nih.gov/pubmed/30006460
http://dx.doi.org/10.1083/jcb.201806127
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author Verlhac, Pauline
Reggiori, Fulvio
author_facet Verlhac, Pauline
Reggiori, Fulvio
author_sort Verlhac, Pauline
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description During micronucleophagy, the nucleolus is targeted by autophagic degradation, but although nucleolar proteins are recycled, ribosomal DNA is spared. Mostofa et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201706164) reveal that the separation of these two nucleolar components is mediated by the CLIP and cohibin complexes and is vital for cell survival during starvation.
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spelling pubmed-60809332019-02-06 Sorting the trash: Micronucleophagy gets selective Verlhac, Pauline Reggiori, Fulvio J Cell Biol Commentaries During micronucleophagy, the nucleolus is targeted by autophagic degradation, but although nucleolar proteins are recycled, ribosomal DNA is spared. Mostofa et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201706164) reveal that the separation of these two nucleolar components is mediated by the CLIP and cohibin complexes and is vital for cell survival during starvation. Rockefeller University Press 2018-08-06 /pmc/articles/PMC6080933/ /pubmed/30006460 http://dx.doi.org/10.1083/jcb.201806127 Text en © 2018 Verlhac and Reggiori http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Verlhac, Pauline
Reggiori, Fulvio
Sorting the trash: Micronucleophagy gets selective
title Sorting the trash: Micronucleophagy gets selective
title_full Sorting the trash: Micronucleophagy gets selective
title_fullStr Sorting the trash: Micronucleophagy gets selective
title_full_unstemmed Sorting the trash: Micronucleophagy gets selective
title_short Sorting the trash: Micronucleophagy gets selective
title_sort sorting the trash: micronucleophagy gets selective
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080933/
https://www.ncbi.nlm.nih.gov/pubmed/30006460
http://dx.doi.org/10.1083/jcb.201806127
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