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Microtubules assemble near most kinetochores during early prometaphase in human cells
For proper segregation during cell division, each chromosome must connect to the poles of the spindle via microtubule bundles termed kinetochore fibers (K-fibers). K-fibers form by two distinct mechanisms: (1) capture of astral microtubules nucleated at the centrosome by the chromosomes’ kinetochore...
Autores principales: | Sikirzhytski, Vitali, Renda, Fioranna, Tikhonenko, Irina, Magidson, Valentin, McEwen, Bruce F., Khodjakov, Alexey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080938/ https://www.ncbi.nlm.nih.gov/pubmed/29907657 http://dx.doi.org/10.1083/jcb.201710094 |
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