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Integrin α4β7 switches its ligand specificity via distinct conformer-specific activation

Chemokine (C-C motif) ligand 25 (CCL25) and C-X-C motif chemokine 10 (CXCL10) induce the ligand-specific activation of integrin α4β7 to mediate the selective adhesion of lymphocytes to mucosal vascular addressin cell adhesion molecule-1 (MAdCAM-1) or vascular cell adhesion molecule-1 (VCAM-1). Howev...

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Detalles Bibliográficos
Autores principales:	Wang, ShiHui, Wu, ChenYu, Zhang, YueBin, Zhong, QingLu, Sun, Hao, Cao, WenPeng, Ge, GaoXiang, Li, GuoHui, Zhang, X. Frank, Chen, JianFeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080939/ https://www.ncbi.nlm.nih.gov/pubmed/29789438 http://dx.doi.org/10.1083/jcb.201710022

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