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Microtubules grow by the addition of bent guanosine triphosphate tubulin to the tips of curved protofilaments
We used electron tomography to examine microtubules (MTs) growing from pure tubulin in vitro as well as two classes of MTs growing in cells from six species. The tips of all these growing MTs display bent protofilaments (PFs) that curve away from the MT axis, in contrast with previously reported MTs...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080942/ https://www.ncbi.nlm.nih.gov/pubmed/29794031 http://dx.doi.org/10.1083/jcb.201802138 |