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Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas

Meningeal melanocytomas are rare pigmented tumors affecting the central nervous system and developing in the cerebrospinal leptomeninges. We report two cases of meningeal melanocytomas showing very marked disparity in their evolution: a very long-term development of meningocerebral lesion, with mali...

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Detalles Bibliográficos
Autores principales: Khoulali, Mohamed, Haouas, Mohammed Yasssine, Mortada, Jihad, Srour, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080982/
https://www.ncbi.nlm.nih.gov/pubmed/30100965
http://dx.doi.org/10.11604/pamj.2018.29.211.10680
Descripción
Sumario:Meningeal melanocytomas are rare pigmented tumors affecting the central nervous system and developing in the cerebrospinal leptomeninges. We report two cases of meningeal melanocytomas showing very marked disparity in their evolution: a very long-term development of meningocerebral lesion, with malignant transformation resulting in the death of the first patient after 32 years and intramedullary ectopic location with very fast massive meningeal diffusion in the second patient. These two cases show the uncertain evolutive profile of meningeal melanocytomas. These lesions may become aggressive with poor prognosis despite an intensive therapeutic strategy.