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Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas

Meningeal melanocytomas are rare pigmented tumors affecting the central nervous system and developing in the cerebrospinal leptomeninges. We report two cases of meningeal melanocytomas showing very marked disparity in their evolution: a very long-term development of meningocerebral lesion, with mali...

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Autores principales: Khoulali, Mohamed, Haouas, Mohammed Yasssine, Mortada, Jihad, Srour, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080982/
https://www.ncbi.nlm.nih.gov/pubmed/30100965
http://dx.doi.org/10.11604/pamj.2018.29.211.10680
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author Khoulali, Mohamed
Haouas, Mohammed Yasssine
Mortada, Jihad
Srour, Robin
author_facet Khoulali, Mohamed
Haouas, Mohammed Yasssine
Mortada, Jihad
Srour, Robin
author_sort Khoulali, Mohamed
collection PubMed
description Meningeal melanocytomas are rare pigmented tumors affecting the central nervous system and developing in the cerebrospinal leptomeninges. We report two cases of meningeal melanocytomas showing very marked disparity in their evolution: a very long-term development of meningocerebral lesion, with malignant transformation resulting in the death of the first patient after 32 years and intramedullary ectopic location with very fast massive meningeal diffusion in the second patient. These two cases show the uncertain evolutive profile of meningeal melanocytomas. These lesions may become aggressive with poor prognosis despite an intensive therapeutic strategy.
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spelling pubmed-60809822018-08-10 Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas Khoulali, Mohamed Haouas, Mohammed Yasssine Mortada, Jihad Srour, Robin Pan Afr Med J Case Report Meningeal melanocytomas are rare pigmented tumors affecting the central nervous system and developing in the cerebrospinal leptomeninges. We report two cases of meningeal melanocytomas showing very marked disparity in their evolution: a very long-term development of meningocerebral lesion, with malignant transformation resulting in the death of the first patient after 32 years and intramedullary ectopic location with very fast massive meningeal diffusion in the second patient. These two cases show the uncertain evolutive profile of meningeal melanocytomas. These lesions may become aggressive with poor prognosis despite an intensive therapeutic strategy. The African Field Epidemiology Network 2018-04-11 /pmc/articles/PMC6080982/ /pubmed/30100965 http://dx.doi.org/10.11604/pamj.2018.29.211.10680 Text en © Mohamed Khoulali et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Khoulali, Mohamed
Haouas, Mohammed Yasssine
Mortada, Jihad
Srour, Robin
Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas
title Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas
title_full Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas
title_fullStr Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas
title_full_unstemmed Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas
title_short Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas
title_sort mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080982/
https://www.ncbi.nlm.nih.gov/pubmed/30100965
http://dx.doi.org/10.11604/pamj.2018.29.211.10680
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