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Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas
Meningeal melanocytomas are rare pigmented tumors affecting the central nervous system and developing in the cerebrospinal leptomeninges. We report two cases of meningeal melanocytomas showing very marked disparity in their evolution: a very long-term development of meningocerebral lesion, with mali...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080982/ https://www.ncbi.nlm.nih.gov/pubmed/30100965 http://dx.doi.org/10.11604/pamj.2018.29.211.10680 |
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author | Khoulali, Mohamed Haouas, Mohammed Yasssine Mortada, Jihad Srour, Robin |
author_facet | Khoulali, Mohamed Haouas, Mohammed Yasssine Mortada, Jihad Srour, Robin |
author_sort | Khoulali, Mohamed |
collection | PubMed |
description | Meningeal melanocytomas are rare pigmented tumors affecting the central nervous system and developing in the cerebrospinal leptomeninges. We report two cases of meningeal melanocytomas showing very marked disparity in their evolution: a very long-term development of meningocerebral lesion, with malignant transformation resulting in the death of the first patient after 32 years and intramedullary ectopic location with very fast massive meningeal diffusion in the second patient. These two cases show the uncertain evolutive profile of meningeal melanocytomas. These lesions may become aggressive with poor prognosis despite an intensive therapeutic strategy. |
format | Online Article Text |
id | pubmed-6080982 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-60809822018-08-10 Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas Khoulali, Mohamed Haouas, Mohammed Yasssine Mortada, Jihad Srour, Robin Pan Afr Med J Case Report Meningeal melanocytomas are rare pigmented tumors affecting the central nervous system and developing in the cerebrospinal leptomeninges. We report two cases of meningeal melanocytomas showing very marked disparity in their evolution: a very long-term development of meningocerebral lesion, with malignant transformation resulting in the death of the first patient after 32 years and intramedullary ectopic location with very fast massive meningeal diffusion in the second patient. These two cases show the uncertain evolutive profile of meningeal melanocytomas. These lesions may become aggressive with poor prognosis despite an intensive therapeutic strategy. The African Field Epidemiology Network 2018-04-11 /pmc/articles/PMC6080982/ /pubmed/30100965 http://dx.doi.org/10.11604/pamj.2018.29.211.10680 Text en © Mohamed Khoulali et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Khoulali, Mohamed Haouas, Mohammed Yasssine Mortada, Jihad Srour, Robin Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas |
title | Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas |
title_full | Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas |
title_fullStr | Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas |
title_full_unstemmed | Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas |
title_short | Mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas |
title_sort | mélanocytome méningé: évolution agressive d’une tumeur bénigne: à propos de 2 cas |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080982/ https://www.ncbi.nlm.nih.gov/pubmed/30100965 http://dx.doi.org/10.11604/pamj.2018.29.211.10680 |
work_keys_str_mv | AT khoulalimohamed melanocytomemeningeevolutionagressivedunetumeurbenigneaproposde2cas AT haouasmohammedyasssine melanocytomemeningeevolutionagressivedunetumeurbenigneaproposde2cas AT mortadajihad melanocytomemeningeevolutionagressivedunetumeurbenigneaproposde2cas AT srourrobin melanocytomemeningeevolutionagressivedunetumeurbenigneaproposde2cas |