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Update on Diabetes Diagnosis: A Historical Review of the Dilemma of the Diagnostic Utility of Glycohemoglobin A1c and a Proposal for a Combined Glucose-A1c Diagnostic Method

The role of glycohemoglobin A1c (A1c) for the diagnosis of diabetes has been debated for over three decades. Recently, the American Diabetes Association (ADA) has recommended adding A1c as an additional criterion for diabetes diagnosis. In view of the continued debate about the diagnostic utility of...

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Detalles Bibliográficos
Autores principales: Aldasouqi, Saleh A., Gossain, Ved V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: King Faisal Specialist Hospital and Research Centre 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081036/
https://www.ncbi.nlm.nih.gov/pubmed/22588455
http://dx.doi.org/10.5144/0256-4947.2012.229
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author Aldasouqi, Saleh A.
Gossain, Ved V.
author_facet Aldasouqi, Saleh A.
Gossain, Ved V.
author_sort Aldasouqi, Saleh A.
collection PubMed
description The role of glycohemoglobin A1c (A1c) for the diagnosis of diabetes has been debated for over three decades. Recently, the American Diabetes Association (ADA) has recommended adding A1c as an additional criterion for diabetes diagnosis. In view of the continued debate about the diagnostic utility of A1c, and in view of the unabated burden of undiagnosed diabetes, the search for alternative diagnostic methods is discussed. A historical literature review is provided, in view of the new ADA diagnostic guidelines, and a proposal is provided for combining A1c and a glucose measurement as a diagnostic alternative/adjunct to the use of a single criterion. This proposal is based on the non-overlapping of the advantages and disadvantages of these individual tests. The cost-effectiveness of this method remains to be tested.
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spelling pubmed-60810362018-09-21 Update on Diabetes Diagnosis: A Historical Review of the Dilemma of the Diagnostic Utility of Glycohemoglobin A1c and a Proposal for a Combined Glucose-A1c Diagnostic Method Aldasouqi, Saleh A. Gossain, Ved V. Ann Saudi Med Review The role of glycohemoglobin A1c (A1c) for the diagnosis of diabetes has been debated for over three decades. Recently, the American Diabetes Association (ADA) has recommended adding A1c as an additional criterion for diabetes diagnosis. In view of the continued debate about the diagnostic utility of A1c, and in view of the unabated burden of undiagnosed diabetes, the search for alternative diagnostic methods is discussed. A historical literature review is provided, in view of the new ADA diagnostic guidelines, and a proposal is provided for combining A1c and a glucose measurement as a diagnostic alternative/adjunct to the use of a single criterion. This proposal is based on the non-overlapping of the advantages and disadvantages of these individual tests. The cost-effectiveness of this method remains to be tested. King Faisal Specialist Hospital and Research Centre 2012 /pmc/articles/PMC6081036/ /pubmed/22588455 http://dx.doi.org/10.5144/0256-4947.2012.229 Text en Copyright © 2012, Annals of Saudi Medicine This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Review
Aldasouqi, Saleh A.
Gossain, Ved V.
Update on Diabetes Diagnosis: A Historical Review of the Dilemma of the Diagnostic Utility of Glycohemoglobin A1c and a Proposal for a Combined Glucose-A1c Diagnostic Method
title Update on Diabetes Diagnosis: A Historical Review of the Dilemma of the Diagnostic Utility of Glycohemoglobin A1c and a Proposal for a Combined Glucose-A1c Diagnostic Method
title_full Update on Diabetes Diagnosis: A Historical Review of the Dilemma of the Diagnostic Utility of Glycohemoglobin A1c and a Proposal for a Combined Glucose-A1c Diagnostic Method
title_fullStr Update on Diabetes Diagnosis: A Historical Review of the Dilemma of the Diagnostic Utility of Glycohemoglobin A1c and a Proposal for a Combined Glucose-A1c Diagnostic Method
title_full_unstemmed Update on Diabetes Diagnosis: A Historical Review of the Dilemma of the Diagnostic Utility of Glycohemoglobin A1c and a Proposal for a Combined Glucose-A1c Diagnostic Method
title_short Update on Diabetes Diagnosis: A Historical Review of the Dilemma of the Diagnostic Utility of Glycohemoglobin A1c and a Proposal for a Combined Glucose-A1c Diagnostic Method
title_sort update on diabetes diagnosis: a historical review of the dilemma of the diagnostic utility of glycohemoglobin a1c and a proposal for a combined glucose-a1c diagnostic method
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081036/
https://www.ncbi.nlm.nih.gov/pubmed/22588455
http://dx.doi.org/10.5144/0256-4947.2012.229
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