Cyclosporin A-related cerebral venous sinus thrombosis: A case report

RATIONALE: Cerebral venous sinus thrombosis (CVST) is a complex life-threatening condition, and its etiology is not well understood. Although oral cyclosporin A is not a common cause of the symptoms related to CVST, there is limited information available. PATIENT CONCERNS: In this study, we report a rare case of CVST in a 44-year-old woman with aplastic anemia, who was given cyclosporin A orally for a period of 18 months. She had experienced a headache for 20 days. DIAGNOSES: The patient was diagnosed with CVST by computed tomography venography. INTERVENTIONS: Low molecular heparin (enoxaparin, 4000 AXaIU, subcutaneous injection, once every 12 hours) was administered for anticoagulation. OUTCOMES: The patient developed no recurrence of thrombosis during the 13-month follow-up period. LESSONS: Clinicians should be aware of the possibility of CVST when patients are treated with cyclosporin A and have symptoms such as headaches.