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Modified unilateral video-assisted thoracoscopic extended thymectomy for myasthenia gravis using 5-mm incisions: A case report

RATIONALE: Myasthenia gravis (MG) is the most common cause of acquired neuromuscular junction disorder. Thymectomy has been established as an effective therapy for MG, as it attenuates the natural course of the disease and may result in complete remission. PATIENT CONCERNS: We report the case of a 2...

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Autores principales: Fan, Ping-Ming, Chen, Guo-Ping, Jiang, Chao-Na, Lv, Peng-Fei, Li, Jing-Tai, Chen, Zhi-Lin, Zheng, Li-Ping, Su, Jie-Zhi, Zheng, Wu-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081170/
https://www.ncbi.nlm.nih.gov/pubmed/30075494
http://dx.doi.org/10.1097/MD.0000000000011237
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author Fan, Ping-Ming
Chen, Guo-Ping
Jiang, Chao-Na
Lv, Peng-Fei
Li, Jing-Tai
Chen, Zhi-Lin
Zheng, Li-Ping
Su, Jie-Zhi
Zheng, Wu-Ping
author_facet Fan, Ping-Ming
Chen, Guo-Ping
Jiang, Chao-Na
Lv, Peng-Fei
Li, Jing-Tai
Chen, Zhi-Lin
Zheng, Li-Ping
Su, Jie-Zhi
Zheng, Wu-Ping
author_sort Fan, Ping-Ming
collection PubMed
description RATIONALE: Myasthenia gravis (MG) is the most common cause of acquired neuromuscular junction disorder. Thymectomy has been established as an effective therapy for MG, as it attenuates the natural course of the disease and may result in complete remission. PATIENT CONCERNS: We report the case of a 22-year-old female with a 6-year history of MG presented with bilateral ptosis, diplopia, and intermittent dysphagia. She denied shortness of breath, dysarthria, and fatigue. DIAGNOSES: She had been diagnosed with MG 6 years previously at the Neurology Department of our hospital. A computed tomography (CT) scan revealed thymic hyperplasia INTERVENTIONS: She was treated with modified unilateral VATET that minimized incision size. OUTCOMES: Unilateral VATET was performed using two 5-mm incisions to minimize pressure on intercostal soft tissues/nerves and reduce postoperative pain. LESSONS: The lesson learnt from this case report is that this modified VATET method could be a useful approach to the management of non-thymomatous MG. The ability to achieve complete dissection with good cosmetic results may lead to wider acceptance of this technique by patients with MG and their neurologists for earlier thymectomy and improved outcomes. Additional studies are needed to determine the superiority of this approach to established methods.
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spelling pubmed-60811702018-08-17 Modified unilateral video-assisted thoracoscopic extended thymectomy for myasthenia gravis using 5-mm incisions: A case report Fan, Ping-Ming Chen, Guo-Ping Jiang, Chao-Na Lv, Peng-Fei Li, Jing-Tai Chen, Zhi-Lin Zheng, Li-Ping Su, Jie-Zhi Zheng, Wu-Ping Medicine (Baltimore) Research Article RATIONALE: Myasthenia gravis (MG) is the most common cause of acquired neuromuscular junction disorder. Thymectomy has been established as an effective therapy for MG, as it attenuates the natural course of the disease and may result in complete remission. PATIENT CONCERNS: We report the case of a 22-year-old female with a 6-year history of MG presented with bilateral ptosis, diplopia, and intermittent dysphagia. She denied shortness of breath, dysarthria, and fatigue. DIAGNOSES: She had been diagnosed with MG 6 years previously at the Neurology Department of our hospital. A computed tomography (CT) scan revealed thymic hyperplasia INTERVENTIONS: She was treated with modified unilateral VATET that minimized incision size. OUTCOMES: Unilateral VATET was performed using two 5-mm incisions to minimize pressure on intercostal soft tissues/nerves and reduce postoperative pain. LESSONS: The lesson learnt from this case report is that this modified VATET method could be a useful approach to the management of non-thymomatous MG. The ability to achieve complete dissection with good cosmetic results may lead to wider acceptance of this technique by patients with MG and their neurologists for earlier thymectomy and improved outcomes. Additional studies are needed to determine the superiority of this approach to established methods. Wolters Kluwer Health 2018-08-03 /pmc/articles/PMC6081170/ /pubmed/30075494 http://dx.doi.org/10.1097/MD.0000000000011237 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle Research Article
Fan, Ping-Ming
Chen, Guo-Ping
Jiang, Chao-Na
Lv, Peng-Fei
Li, Jing-Tai
Chen, Zhi-Lin
Zheng, Li-Ping
Su, Jie-Zhi
Zheng, Wu-Ping
Modified unilateral video-assisted thoracoscopic extended thymectomy for myasthenia gravis using 5-mm incisions: A case report
title Modified unilateral video-assisted thoracoscopic extended thymectomy for myasthenia gravis using 5-mm incisions: A case report
title_full Modified unilateral video-assisted thoracoscopic extended thymectomy for myasthenia gravis using 5-mm incisions: A case report
title_fullStr Modified unilateral video-assisted thoracoscopic extended thymectomy for myasthenia gravis using 5-mm incisions: A case report
title_full_unstemmed Modified unilateral video-assisted thoracoscopic extended thymectomy for myasthenia gravis using 5-mm incisions: A case report
title_short Modified unilateral video-assisted thoracoscopic extended thymectomy for myasthenia gravis using 5-mm incisions: A case report
title_sort modified unilateral video-assisted thoracoscopic extended thymectomy for myasthenia gravis using 5-mm incisions: a case report
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081170/
https://www.ncbi.nlm.nih.gov/pubmed/30075494
http://dx.doi.org/10.1097/MD.0000000000011237
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