Cargando…

Precardiac organoids form two heart fields via Bmp/Wnt signaling

The discovery of the first heart field (FHF) and the second heart field (SHF) led us to understand how cardiac lineages and structures arise during development. However, it remains unknown how they are specified. Here, we generate precardiac spheroids with pluripotent stem cells (PSCs) harboring GFP...

Descripción completa

Detalles Bibliográficos
Autores principales:	Andersen, Peter, Tampakakis, Emmanouil, Jimenez, Dennisse V., Kannan, Suraj, Miyamoto, Matthew, Shin, Hye Kyung, Saberi, Amir, Murphy, Sean, Sulistio, Edrick, Chelko, Stephen P., Kwon, Chulan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081372/ https://www.ncbi.nlm.nih.gov/pubmed/30087351 http://dx.doi.org/10.1038/s41467-018-05604-8

Ejemplares similares

Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitors
por: Shenje, Lincoln T, et al.
Publicado: (2014)

Cardiac progenitors instruct second heart field fate through Wnts
por: Miyamoto, Matthew, et al.
Publicado: (2023)

Heart neurons use clock genes to control myocyte proliferation
por: Tampakakis, Emmanouil, et al.
Publicado: (2021)

PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2
por: Murphy, Sean A., et al.
Publicado: (2021)

Transcriptomic entropy benchmarks stem cell-derived cardiomyocyte maturation against endogenous tissue at single cell level
por: Kannan, Suraj, et al.
Publicado: (2021)

Wnt + BMP = stem cell
por: LeBrasseur, Nicole
Publicado: (2005)

Asymmetric BMP4 signalling improves the realism of kidney organoids
por: Mills, Christopher G., et al.
Publicado: (2017)

Sympathetic Neurons Regulate Cardiomyocyte Maturation in Culture
por: Kowalski, William J., et al.
Publicado: (2022)

Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling
por: Kléber, Maurice, et al.
Publicado: (2005)

A BMP-2–triggered in vivo osteo-organoid for cell therapy
por: Dai, Kai, et al.
Publicado: (2023)

Trajectory reconstruction identifies dysregulation of perinatal maturation programs in pluripotent stem cell-derived cardiomyocytes
por: Kannan, Suraj, et al.
Publicado: (2023)

MeCP2 dysfunction prevents proper BMP signaling and neural progenitor expansion in brain organoid
por: Hong, Hyowon, et al.
Publicado: (2023)

The Wnt and BMP Families of Signaling Morphogens at the Vertebrate Neuromuscular Junction
por: Henríquez, Juan P., et al.
Publicado: (2011)

Ocular surface ectoderm instigated by WNT inhibition and BMP4
por: Kobayashi, Yuki, et al.
Publicado: (2020)

Dysregulation of BMP, Wnt, and Insulin Signaling in Fragile X Syndrome
por: Song, Chunzhu, et al.
Publicado: (2022)

Canonical Wnt signalling requires the BMP pathway to inhibit oligodendrocyte maturation
por: Feigenson, Keith, et al.
Publicado: (2011)

Temporal and contextual orchestration of cardiac fate by WNT-BMP synergy and threshold
por: Verma, Mahesh K, et al.
Publicado: (2010)

Sequential and Opposing Activities of Wnt and BMP Coordinate Zebrafish Bone Regeneration
por: Stewart, Scott, et al.
Publicado: (2014)

Functional interaction between Wnt and Bmp signaling in periosteal bone growth
por: Song, Deye, et al.
Publicado: (2021)

Sulfated Polysaccharide Regulates the Homing of HSPCs in a BMP‐2‐Triggered In Vivo Osteo‐Organoid
por: Dai, Kai, et al.
Publicado: (2023)

Kidney Organoids Are Capable of Forming Tumors, but Not Teratomas
por: Shankar, Anusha S, et al.
Publicado: (2022)

Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms
por: Salmon, Richard M., et al.
Publicado: (2020)

Human colon organoids reveal distinct physiologic and oncogenic Wnt responses
por: Michels, Birgitta E., et al.
Publicado: (2019)

Early Development of the Central and Peripheral Nervous Systems Is Coordinated by Wnt and BMP Signals
por: Patthey, Cédric, et al.
Publicado: (2008)

Urinary excretion of RAS, BMP, and WNT pathway components in diabetic kidney disease
por: Afkarian, Maryam, et al.
Publicado: (2014)

Restricted Adipogenesis in Hypertrophic Obesity: The Role of WISP2, WNT, and BMP4
por: Gustafson, Birgit, et al.
Publicado: (2013)

Endoglin integrates BMP and Wnt signalling to induce haematopoiesis through JDP2
por: Baik, June, et al.
Publicado: (2016)

BMP3 expression by osteoblast lineage cells is regulated by canonical Wnt signaling
por: Kokabu, Shoichiro, et al.
Publicado: (2017)

YAP promotes neural crest emigration through interactions with BMP and Wnt activities
por: Kumar, Deepak, et al.
Publicado: (2019)

BMP suppresses WNT to integrate patterning of orthogonal body axes in adult planarians
por: Clark, Eleanor G., et al.
Publicado: (2023)

BMP suppresses WNT to integrate patterning of orthogonal body axes in adult planarians
por: Clark, Eleanor G., et al.
Publicado: (2023)

Acceleration of osteoblast differentiation by a novel osteogenic compound, DMP-PYT, through activation of both the BMP and Wnt pathways
por: Bae, Su Jung, et al.
Publicado: (2017)

Multiplatform modeling of atrial fibrillation identifies phospholamban as a central regulator of cardiac rhythm
por: Kervadec, Anaïs, et al.
Publicado: (2023)

Human Blood Vessel Organoids Penetrate Human Cerebral Organoids and Form a Vessel-Like System
por: Ahn, Yujin, et al.
Publicado: (2021)

The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids
por: Kessler, Mirjana, et al.
Publicado: (2015)

Aspirin Rescues Wnt-Driven Stem-like Phenotype in Human Intestinal Organoids and Increases the Wnt Antagonist Dickkopf-1
por: Dunbar, Karen, et al.
Publicado: (2020)

Organoid modelling identifies that DACH1 functions as a tumour promoter in colorectal cancer by modulating BMP signalling
por: Hu, Xiang, et al.
Publicado: (2020)

Holoprosencephaly with a Special Form of Anophthalmia Result from Experimental Induction of bmp4, Oversaturating BMP Antagonists in Zebrafish
por: Bulk, Johannes, et al.
Publicado: (2023)

Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury
por: Dell'Accio, Francesco, et al.
Publicado: (2006)

Endocardial to Myocardial Notch-Wnt-Bmp Axis Regulates Early Heart Valve Development
por: Wang, Yidong, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_mnkfltalgtshugo6ltshc8jkji