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Oligomerization of bacterially expressed H1N1 recombinant hemagglutinin contributes to protection against viral challenge

Vaccination is the most effective intervention to prevent influenza and control the spread of the virus. Alternatives are needed to the traditional egg-based vaccine strategy for a more rapid response to new outbreaks. Two different hemagglutinin (HA) fragments (rHA1(1-326) and rHA1(53-269)) derived...

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Detalles Bibliográficos
Autores principales: Kuenstling, Tess E., Sambol, Anthony R., Hinrichs, Steven H., Larson, Marilynn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081378/
https://www.ncbi.nlm.nih.gov/pubmed/30087372
http://dx.doi.org/10.1038/s41598-018-30079-4

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