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Reduced post-operative DPP4 activity associated with worse patient outcome after cardiac surgery

Cardiac surgery with cardiopulmonary bypass (CPB) triggers myocardial ischemia/reperfusion injury contributing to organ dysfunction. Preclinical studies revealed that dipeptidyl peptidase (DPP4) inhibition is protective during myocardial infarction. Here, we assessed for the first time the relation...

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Detalles Bibliográficos
Autores principales: Noels, Heidi, Theelen, Wendy, Sternkopf, Marieke, Jankowski, Vera, Moellmann, Julia, Kraemer, Sandra, Lehrke, Michael, Marx, Nikolaus, Martin, Lukas, Marx, Gernot, Jankowski, Joachim, Goetzenich, Andreas, Stoppe, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081383/
https://www.ncbi.nlm.nih.gov/pubmed/30087386
http://dx.doi.org/10.1038/s41598-018-30235-w