Formulation, characterization and evaluation of mRNA-loaded dissolvable polymeric microneedles (RNApatch)

In this paper, we report a proof of concept study on the fabrication, characterization and therapeutic evaluation of in vitro transcribed messenger RNA (mRNA) loaded in a dissolving microneedle patch (RNApatch). We show that low molecular weight polyvinylpyrrolidone (PVP) can directly be used withou...

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Detalles Bibliográficos
Autores principales: Koh, Kai Jun, Liu, Yi, Lim, Seng Han, Loh, Xian Jun, Kang, Lifeng, Lim, Chee Yen, Phua, Kyle K. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081392/
https://www.ncbi.nlm.nih.gov/pubmed/30087399
http://dx.doi.org/10.1038/s41598-018-30290-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081392/
https://www.ncbi.nlm.nih.gov/pubmed/30087399
http://dx.doi.org/10.1038/s41598-018-30290-3

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