Cargando…
Formulation, characterization and evaluation of mRNA-loaded dissolvable polymeric microneedles (RNApatch)
In this paper, we report a proof of concept study on the fabrication, characterization and therapeutic evaluation of in vitro transcribed messenger RNA (mRNA) loaded in a dissolving microneedle patch (RNApatch). We show that low molecular weight polyvinylpyrrolidone (PVP) can directly be used withou...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081392/ https://www.ncbi.nlm.nih.gov/pubmed/30087399 http://dx.doi.org/10.1038/s41598-018-30290-3 |