Sequence analysis of integrated hepatitis B virus DNA during HBeAg-seroconversion

Hepatitis B virus (HBV) integration into the host cell genome occurs early on in infection and reportedly induces pro-oncogenic changes in hepatocytes that drive HCC initiation. However, it remains unclear when these changes occur during hepatocarcinogenesis. Extensive expansion of hepatocyte clones...

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Detalles Bibliográficos
Autores principales: Budzinska, Magdalena Agnieszka, Shackel, Nicholas Adam, Urban, Stephan, Tu, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081408/
https://www.ncbi.nlm.nih.gov/pubmed/30087321
http://dx.doi.org/10.1038/s41426-018-0145-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081408/
https://www.ncbi.nlm.nih.gov/pubmed/30087321
http://dx.doi.org/10.1038/s41426-018-0145-7

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