HER2 Basolateral versus Circumferential IHC Expression Is Dependent on Polarity and Differentiation of Epithelial Cells in Gastric/GE Adenocarcinoma

AIM: Antigenic expression in epithelial cells can be heterogeneous which may pose a problem in immunohistochemical (IHC) analysis of tumor markers, in particular, predictive markers like HER2. Studies have shown that epithelial cells have distinct apical and basolateral domains which are separated b...

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Detalles Bibliográficos
Autores principales: Pervez, Shahid, Arshad, Sidra, Abro, Brooj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081602/
https://www.ncbi.nlm.nih.gov/pubmed/30140423
http://dx.doi.org/10.1155/2018/6246493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081602/
https://www.ncbi.nlm.nih.gov/pubmed/30140423
http://dx.doi.org/10.1155/2018/6246493

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