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Greater tau load and reduced cortical thickness in APOE ε4-negative Alzheimer’s disease: a cohort study

BACKGROUND: Alzheimer’s disease is characterized by aggregated β-amyloid and tau proteins, but the clinical presentations and patterns of brain atrophy vary substantially. A part of this heterogeneity may be linked to the risk allele APOE ε4. The spread of tau pathology is related to atrophy and cog...

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Detalles Bibliográficos
Autores principales:	Mattsson, Niklas, Ossenkoppele, Rik, Smith, Ruben, Strandberg, Olof, Ohlsson, Tomas, Jögi, Jonas, Palmqvist, Sebastian, Stomrud, Erik, Hansson, Oskar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081879/ https://www.ncbi.nlm.nih.gov/pubmed/30086796 http://dx.doi.org/10.1186/s13195-018-0403-x

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