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Antibiotic Susceptibility Monitoring of Neisseria gonorrhoeae in Bacolod City, Philippines

A local study was conducted to monitor the antibiotic susceptibility of N. gonorrhoeae in Bacolod City, Philippines. A total of 88 isolates were taken during the period of 1 January 2015 to 30 June 2017, from male patients ages 12 to 72 years. The highest incidence of gonorrhea infection was in the...

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Autores principales: Araneta, Clark Martin P., Juayang, Alain C., Lim, Joseph Peter T., Quilop, Eleeza Marie G., Casaysay, Nadine Joy G., Tamesis, Gene Marie L., Yude, Tricia Marie G., Romero, Sarah Joyce E., Gayoba, Raziel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082094/
https://www.ncbi.nlm.nih.gov/pubmed/30270902
http://dx.doi.org/10.3390/tropicalmed2030045
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author Araneta, Clark Martin P.
Juayang, Alain C.
Lim, Joseph Peter T.
Quilop, Eleeza Marie G.
Casaysay, Nadine Joy G.
Tamesis, Gene Marie L.
Yude, Tricia Marie G.
Romero, Sarah Joyce E.
Gayoba, Raziel C.
author_facet Araneta, Clark Martin P.
Juayang, Alain C.
Lim, Joseph Peter T.
Quilop, Eleeza Marie G.
Casaysay, Nadine Joy G.
Tamesis, Gene Marie L.
Yude, Tricia Marie G.
Romero, Sarah Joyce E.
Gayoba, Raziel C.
author_sort Araneta, Clark Martin P.
collection PubMed
description A local study was conducted to monitor the antibiotic susceptibility of N. gonorrhoeae in Bacolod City, Philippines. A total of 88 isolates were taken during the period of 1 January 2015 to 30 June 2017, from male patients ages 12 to 72 years. The highest incidence of gonorrhea infection was in the group aged 20–24 years (34.09%). The susceptibility pattern to antibiotics was as follows: ceftriaxone 100%, cefixime 82.6%, spectinomycin 92.1%, ciprofloxacin 4.9%, tetracycline 5.1%, and penicillin G with 0%. All isolates were noted to produce beta-lactamase, which can be attributed to plasmid-mediated penicillin resistance. These findings indicate that the resistance rates of N. gonorrhoeae to most commonly-used antibiotics are increasing, and that ceftriaxone remains an effective antibiotic in treating gonorrhea infections locally.
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spelling pubmed-60820942018-09-24 Antibiotic Susceptibility Monitoring of Neisseria gonorrhoeae in Bacolod City, Philippines Araneta, Clark Martin P. Juayang, Alain C. Lim, Joseph Peter T. Quilop, Eleeza Marie G. Casaysay, Nadine Joy G. Tamesis, Gene Marie L. Yude, Tricia Marie G. Romero, Sarah Joyce E. Gayoba, Raziel C. Trop Med Infect Dis Article A local study was conducted to monitor the antibiotic susceptibility of N. gonorrhoeae in Bacolod City, Philippines. A total of 88 isolates were taken during the period of 1 January 2015 to 30 June 2017, from male patients ages 12 to 72 years. The highest incidence of gonorrhea infection was in the group aged 20–24 years (34.09%). The susceptibility pattern to antibiotics was as follows: ceftriaxone 100%, cefixime 82.6%, spectinomycin 92.1%, ciprofloxacin 4.9%, tetracycline 5.1%, and penicillin G with 0%. All isolates were noted to produce beta-lactamase, which can be attributed to plasmid-mediated penicillin resistance. These findings indicate that the resistance rates of N. gonorrhoeae to most commonly-used antibiotics are increasing, and that ceftriaxone remains an effective antibiotic in treating gonorrhea infections locally. MDPI 2017-08-29 /pmc/articles/PMC6082094/ /pubmed/30270902 http://dx.doi.org/10.3390/tropicalmed2030045 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Araneta, Clark Martin P.
Juayang, Alain C.
Lim, Joseph Peter T.
Quilop, Eleeza Marie G.
Casaysay, Nadine Joy G.
Tamesis, Gene Marie L.
Yude, Tricia Marie G.
Romero, Sarah Joyce E.
Gayoba, Raziel C.
Antibiotic Susceptibility Monitoring of Neisseria gonorrhoeae in Bacolod City, Philippines
title Antibiotic Susceptibility Monitoring of Neisseria gonorrhoeae in Bacolod City, Philippines
title_full Antibiotic Susceptibility Monitoring of Neisseria gonorrhoeae in Bacolod City, Philippines
title_fullStr Antibiotic Susceptibility Monitoring of Neisseria gonorrhoeae in Bacolod City, Philippines
title_full_unstemmed Antibiotic Susceptibility Monitoring of Neisseria gonorrhoeae in Bacolod City, Philippines
title_short Antibiotic Susceptibility Monitoring of Neisseria gonorrhoeae in Bacolod City, Philippines
title_sort antibiotic susceptibility monitoring of neisseria gonorrhoeae in bacolod city, philippines
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082094/
https://www.ncbi.nlm.nih.gov/pubmed/30270902
http://dx.doi.org/10.3390/tropicalmed2030045
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