Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts

Preclinical models based on patient-derived xenografts have remarkable specificity in distinguishing transformed human tumor cells from non-transformed murine stromal cells computationally. We obtained 29 pancreatic ductal adenocarcinoma (PDAC) xenografts from either resectable or non-resectable pat...

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Detalles Bibliográficos
Autores principales: Nicolle, Rémy, Blum, Yuna, Marisa, Laetitia, Loncle, Celine, Gayet, Odile, Moutardier, Vincent, Turrini, Olivier, Giovannini, Marc, Bian, Benjamin, Bigonnet, Martin, Rubis, Marion, Elarouci, Nabila, Armenoult, Lucile, Ayadi, Mira, Duconseil, Pauline, Gasmi, Mohamed, Ouaissi, Mehdi, Maignan, Aurélie, Lomberk, Gwen, Boher, Jean-Marie, Ewald, Jacques, Bories, Erwan, Garnier, Jonathan, Goncalves, Anthony, Poizat, Flora, Raoul, Jean-Luc, Secq, Veronique, Garcia, Stephane, Grandval, Philippe, Barraud-Blanc, Marine, Norguet, Emmanuelle, Gilabert, Marine, Delpero, Jean-Robert, Roques, Julie, Calvo, Ezequiel, Guillaumond, Fabienne, Vasseur, Sophie, Urrutia, Raul, de Reyniés, Aurélien, Dusetti, Nelson, Iovanna, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082139/
https://www.ncbi.nlm.nih.gov/pubmed/29186684
http://dx.doi.org/10.1016/j.celrep.2017.11.003

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