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Tongue Pressure Sensing Array Integrated with a System-on-Chip Embedded in a Mandibular Advancement Splint

Obstructive sleep apnea (OSA), which is caused by obstructions of the upper airway, is a syndrome with rising prevalence. Mandibular advancement splints (MAS) are oral appliances for potential treatment of OSA. This work proposes a highly-sensitive pressure sensing array integrated with a system-on-...

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Autores principales: Chen, Yun-Ting, Yeh, Kun-Ying, Chen, Szu-Han, Wang, Chuang-Yin, Yeh, Chao-Chi, Xu, Ming-Xin, Lu, Shey-Shi, Chen, Yunn-Jy, Yang, Yao-Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082261/
https://www.ncbi.nlm.nih.gov/pubmed/30424285
http://dx.doi.org/10.3390/mi9070352
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author Chen, Yun-Ting
Yeh, Kun-Ying
Chen, Szu-Han
Wang, Chuang-Yin
Yeh, Chao-Chi
Xu, Ming-Xin
Lu, Shey-Shi
Chen, Yunn-Jy
Yang, Yao-Joe
author_facet Chen, Yun-Ting
Yeh, Kun-Ying
Chen, Szu-Han
Wang, Chuang-Yin
Yeh, Chao-Chi
Xu, Ming-Xin
Lu, Shey-Shi
Chen, Yunn-Jy
Yang, Yao-Joe
author_sort Chen, Yun-Ting
collection PubMed
description Obstructive sleep apnea (OSA), which is caused by obstructions of the upper airway, is a syndrome with rising prevalence. Mandibular advancement splints (MAS) are oral appliances for potential treatment of OSA. This work proposes a highly-sensitive pressure sensing array integrated with a system-on-chip (SoC) embedded in a MAS. The device aims to measure tongue pressure distribution in order to determine the efficacy of the MAS for treating OSA. The flexible sensing array consists of an interdigital electrode pair array assembled with conductive polymer films and an SoC capable of retrieving/storing data during sleep, and transmitting data for analysis after sleep monitoring. The surfaces of the conductive polymer films were patterned with microdomed structures, which effectively increased the sensitivity and reduced the pressure sensing response time. The measured results also show that the crosstalk effect between the sensing elements of the array was negligible. The sensitivity of the sensing array changed minimally after the device was submerged in water for up to 100 h.
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spelling pubmed-60822612018-11-01 Tongue Pressure Sensing Array Integrated with a System-on-Chip Embedded in a Mandibular Advancement Splint Chen, Yun-Ting Yeh, Kun-Ying Chen, Szu-Han Wang, Chuang-Yin Yeh, Chao-Chi Xu, Ming-Xin Lu, Shey-Shi Chen, Yunn-Jy Yang, Yao-Joe Micromachines (Basel) Article Obstructive sleep apnea (OSA), which is caused by obstructions of the upper airway, is a syndrome with rising prevalence. Mandibular advancement splints (MAS) are oral appliances for potential treatment of OSA. This work proposes a highly-sensitive pressure sensing array integrated with a system-on-chip (SoC) embedded in a MAS. The device aims to measure tongue pressure distribution in order to determine the efficacy of the MAS for treating OSA. The flexible sensing array consists of an interdigital electrode pair array assembled with conductive polymer films and an SoC capable of retrieving/storing data during sleep, and transmitting data for analysis after sleep monitoring. The surfaces of the conductive polymer films were patterned with microdomed structures, which effectively increased the sensitivity and reduced the pressure sensing response time. The measured results also show that the crosstalk effect between the sensing elements of the array was negligible. The sensitivity of the sensing array changed minimally after the device was submerged in water for up to 100 h. MDPI 2018-07-14 /pmc/articles/PMC6082261/ /pubmed/30424285 http://dx.doi.org/10.3390/mi9070352 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chen, Yun-Ting
Yeh, Kun-Ying
Chen, Szu-Han
Wang, Chuang-Yin
Yeh, Chao-Chi
Xu, Ming-Xin
Lu, Shey-Shi
Chen, Yunn-Jy
Yang, Yao-Joe
Tongue Pressure Sensing Array Integrated with a System-on-Chip Embedded in a Mandibular Advancement Splint
title Tongue Pressure Sensing Array Integrated with a System-on-Chip Embedded in a Mandibular Advancement Splint
title_full Tongue Pressure Sensing Array Integrated with a System-on-Chip Embedded in a Mandibular Advancement Splint
title_fullStr Tongue Pressure Sensing Array Integrated with a System-on-Chip Embedded in a Mandibular Advancement Splint
title_full_unstemmed Tongue Pressure Sensing Array Integrated with a System-on-Chip Embedded in a Mandibular Advancement Splint
title_short Tongue Pressure Sensing Array Integrated with a System-on-Chip Embedded in a Mandibular Advancement Splint
title_sort tongue pressure sensing array integrated with a system-on-chip embedded in a mandibular advancement splint
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082261/
https://www.ncbi.nlm.nih.gov/pubmed/30424285
http://dx.doi.org/10.3390/mi9070352
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