Relationship between HER2 gene status and selected potential biological features related to trastuzumab resistance and its influence on survival of breast cancer patients undergoing trastuzumab adjuvant treatment

BACKGROUND: The aim of the study was to investigate if parameters associated with human epidermal growth factor receptor type 2 (HER2) status (HER2 gene copy number, HER2/CEP17 ratio or polysomy of chromosome 17) are related to various biological features potentially responsible for trastuzumab resi...

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Detalles Bibliográficos
Autores principales: Adamczyk, Agnieszka, Kruczak, Anna, Harazin-Lechowska, Agnieszka, Ambicka, Aleksandra, Grela-Wojewoda, Aleksandra, Domagała-Haduch, Małgorzata, Janecka-Widła, Anna, Majchrzyk, Kaja, Cichocka, Anna, Ryś, Janusz, Niemiec, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082350/
https://www.ncbi.nlm.nih.gov/pubmed/30122944
http://dx.doi.org/10.2147/OTT.S166983

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