Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer’s disease: A prospective study in eight cohorts

INTRODUCTION: Metabolite, lipid, and lipoprotein lipid profiling can provide novel insights into mechanisms underlying incident dementia and Alzheimer’s disease. METHODS: We studied eight prospective cohorts with 22,623 participants profiled by nuclear magnetic resonance or mass spectrometry metabol...

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Detalles Bibliográficos
Autores principales: Tynkkynen, Juho, Chouraki, Vincent, van der Lee, Sven J., Hernesniemi, Jussi, Yang, Qiong, Li, Shuo, Beiser, Alexa, Larson, Martin G., Söaöaksjöarvi, Katri, Shipley, Martin J., Singh-Manoux, Archana, Gerszten, Robert E., Wang, Thomas J., Havulinna, Aki S., Wöurtz, Peter, Fischer, Krista, Demirkan, Ayse, Ikram, M. Arfan, Amin, Najaf, Lehtimöaki, Terho, Köahöonen, Mika, Perola, Markus, Metspalu, Andres, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Vasan, Ramachandran S., Kivimöaki, Mika, van Duijn, Cornelia M., Seshadri, Sudha, Salomaa, Veikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082422/
https://www.ncbi.nlm.nih.gov/pubmed/29519576
http://dx.doi.org/10.1016/j.jalz.2018.01.003

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