The Fas Signaling Pathway Is a Common Genetic Risk Factor for Severe Cutaneous Drug Adverse Reactions Across Diverse Drugs

PURPOSE: Human leukocyte antigen (HLA) has been recognized as the most important genetic risk factor for severe cutaneous adverse drug reactions (SCARs) caused by certain drugs. However, cumulated observations suggest the presence of genetic risk factors for SCARs other than drug-specific HLA. We ai...

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Detalles Bibliográficos
Autores principales: Park, Heung-Woo, Kim, Sang-Heon, Chang, Yoon-Seok, Kim, Sang-Hoon, Jee, Young-Koo, Lee, Ai-Young, Jang, In-Jin, Park, Hae-Sim, Min, Kyung-Up
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082816/
https://www.ncbi.nlm.nih.gov/pubmed/30088374
http://dx.doi.org/10.4168/aair.2018.10.5.555

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