Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine

The role of somatostatin interneurons in nucleus accumbens (NAc), a key brain reward region, remains poorly understood due to the fact that these cells account for < 1% of NAc neurons. Here, we use optogenetics, electrophysiology, and RNA-sequencing to characterize the transcriptome and functioni...

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Detalles Bibliográficos
Autores principales: Ribeiro, Efrain A., Salery, Marine, Scarpa, Joseph R., Calipari, Erin S., Hamilton, Peter J., Ku, Stacy M., Kronman, Hope, Purushothaman, Immanuel, Juarez, Barbara, Heshmati, Mitra, Doyle, Marie, Lardner, Casey, Burek, Dominicka, Strat, Ana, Pirpinias, Stephen, Mouzon, Ezekiell, Han, Ming-Hu, Neve, Rachael L., Bagot, Rosemary C., Kasarskis, Andrew, Koo, Ja Wook, Nestler, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082848/
https://www.ncbi.nlm.nih.gov/pubmed/30089879
http://dx.doi.org/10.1038/s41467-018-05657-9

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