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Interphase human chromosome exhibits out of equilibrium glassy dynamics
Fingerprints of the three-dimensional organization of genomes have emerged using advances in Hi-C and imaging techniques. However, genome dynamics is poorly understood. Here, we create the chromosome copolymer model (CCM) by representing chromosomes as a copolymer with two epigenetic loci types corr...
Autores principales: | Shi, Guang, Liu, Lei, Hyeon, Changbong, Thirumalai, D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082855/ https://www.ncbi.nlm.nih.gov/pubmed/30089831 http://dx.doi.org/10.1038/s41467-018-05606-6 |
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