LGR5 regulates gastric adenocarcinoma cell proliferation and invasion via activating Wnt signaling pathway

LGR5 plays a critical role in tissue development and the maintenance of adult stem cells in gastrointestinal tract. However, the oncogenic role of LGR5 in the development of gastric adenocarcinoma remains elusive. Here, we show that LGR5 promotes gastric adenocarcinoma cell proliferation and metasta...

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Detalles Bibliográficos
Autores principales: Wang, Xiangfei, Wang, Xiumin, Liu, Yang, Dong, Yating, Wang, Yanan, Kassab, Muzaffer Ahmad, Fan, Wufang, Yu, Xiaochun, Wu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082861/
https://www.ncbi.nlm.nih.gov/pubmed/30089773
http://dx.doi.org/10.1038/s41389-018-0071-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082861/
https://www.ncbi.nlm.nih.gov/pubmed/30089773
http://dx.doi.org/10.1038/s41389-018-0071-5

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