Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny

Antenatal inflammation as seen with chorioamnionitis is harmful to foetal/neonatal organ development including to eyes. Although the major pro-inflammatory cytokine IL-1β participates in retinopathy induced by hyperoxia (a predisposing factor to retinopathy of prematurity), the specific role of ante...

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Detalles Bibliográficos
Autores principales: Beaudry-Richard, Alexandra, Nadeau-Vallée, Mathieu, Prairie, Élizabeth, Maurice, Noémie, Heckel, Émilie, Nezhady, Mohammad, Pundir, Sheetal, Madaan, Ankush, Boudreault, Amarilys, Hou, Xin, Quiniou, Christiane, Sierra, Estefania Marin, Beaulac, Alexandre, Lodygensky, Gregory, Robertson, Sarah A., Keelan, Jeffrey, Adams Waldorf, Kristina M., Olson, David M., Rivera, Jose-Carlos, Lubell, William D., Joyal, Jean-Sebastien, Bouchard, Jean-François, Chemtob, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082873/
https://www.ncbi.nlm.nih.gov/pubmed/30089839
http://dx.doi.org/10.1038/s41598-018-30087-4

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