PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1–Parkin-mediated mitophagy

Mitophagy is an important type of selective autophagy for specific elimination of damaged mitochondria. PTEN-induced putative kinase protein 1 (PINK1)-catalyzed phosphorylation of ubiquitin (Ub) plays a critical role in the onset of PINK1–Parkin-mediated mitophagy. Phosphatase and tensin homolog (PT...

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Detalles Bibliográficos
Autores principales: Wang, Liming, Cho, Yik-Lam, Tang, Yancheng, Wang, Jigang, Park, Jung-Eun, Wu, Yajun, Wang, Chunxin, Tong, Yan, Chawla, Ritu, Zhang, Jianbin, Shi, Yin, Deng, Shuo, Lu, Guang, Wu, Yihua, Tan, Hayden Weng-Siong, Pawijit, Pornteera, Lim, Grace Gui-Yin, Chan, Hui-Ying, Zhang, Jingzi, Fang, Lei, Yu, Hanry, Liou, Yih-Cherng, Karthik, Mallilankaraman, Bay, Boon-Huat, Lim, Kah-Leong, Sze, Siu-Kwan, Yap, Celestial T., Shen, Han-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082900/
https://www.ncbi.nlm.nih.gov/pubmed/29934616
http://dx.doi.org/10.1038/s41422-018-0056-0

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