Protective Regulatory T Cell Immune Response Induced by Intranasal Immunization With the Live-Attenuated Pneumococcal Vaccine SPY1 via the Transforming Growth Factor-β1-Smad2/3 Pathway

Vaccine effectiveness is mainly determined by the mechanism mediating protection, emphasizing the importance of unraveling the protective mechanism for novel pneumococcal vaccine development. We previously demonstrated that the regulatory T cell (Treg) immune response has a protective effect against...

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Detalles Bibliográficos
Autores principales: Liao, Hongyi, Peng, Xiaoqiong, Gan, Lingling, Feng, Jiafu, Gao, Yue, Yang, Shenghui, Hu, Xuexue, Zhang, Liping, Yin, Yibing, Wang, Hong, Xu, Xiuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082925/
https://www.ncbi.nlm.nih.gov/pubmed/30116243
http://dx.doi.org/10.3389/fimmu.2018.01754

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