The p.Arg435His Variation of IgG3 With High Affinity to FcRn Is Associated With Susceptibility for Pemphigus Vulgaris—Analysis of Four Different Ethnic Cohorts

IgG3 is the IgG subclass with the strongest effector functions among all four IgG subclasses and the highest degree of allelic variability among all constant immunoglobulin genes. Due to its genetic position, IgG3 is often the first isotype an antibody switches to before IgG1 or IgG4. Compared with...

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Detalles Bibliográficos
Autores principales: Recke, Andreas, Konitzer, Sarah, Lemcke, Susanne, Freitag, Miriam, Sommer, Nele Maxi, Abdelhady, Mohammad, Amoli, Mahsa M., Benoit, Sandrine, El-Chennawy, Farha, Eldarouti, Mohammad, Eming, Rüdiger, Gläser, Regine, Günther, Claudia, Hadaschik, Eva, Homey, Bernhard, Lieb, Wolfgang, Peitsch, Wiebke K., Pföhler, Claudia, Robati, Reza M., Saeedi, Marjan, Sárdy, Miklós, Sticherling, Michael, Uzun, Soner, Worm, Margitta, Zillikens, Detlef, Ibrahim, Saleh, Vidarsson, Gestur, Schmidt, Enno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082936/
https://www.ncbi.nlm.nih.gov/pubmed/30116249
http://dx.doi.org/10.3389/fimmu.2018.01788

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