Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer

BACKGROUND & AIMS: Chronic inflammation is a predisposing condition for colorectal cancer. Many studies to date have focused on proinflammatory signaling pathways in the colon. Understanding the mechanisms that suppress inflammation, particularly in epithelial cells, is critical for developing t...

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Detalles Bibliográficos
Autores principales: Means, Anna L., Freeman, Tanner J., Zhu, Jing, Woodbury, Luke G., Marincola-Smith, Paula, Wu, Chao, Meyer, Anne R., Weaver, Connie J., Padmanabhan, Chandrasekhar, An, Hanbing, Zi, Jinghuan, Wessinger, Bronson C., Chaturvedi, Rupesh, Brown, Tasia D., Deane, Natasha G., Coffey, Robert J., Wilson, Keith T., Smith, J. Joshua, Sawyers, Charles L., Goldenring, James R., Novitskiy, Sergey V., Washington, M. Kay, Shi, Chanjuan, Beauchamp, R. Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083016/
https://www.ncbi.nlm.nih.gov/pubmed/30109253
http://dx.doi.org/10.1016/j.jcmgh.2018.05.006

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