Combining mGRASP and Optogenetics Enables High-Resolution Functional Mapping of Descending Cortical Projections

We have applied optogenetics and mGRASP, a light microscopy technique that labels synaptic contacts, to map the number and strength of defined corticocollicular (CC) connections. Using mGRASP, we show that CC projections form small, medium, and large synapses, and both the number and the distributio...

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Detalles Bibliográficos
Autores principales: Song, Jun Ho, Lucaci, Diana, Calangiu, Ioana, Brown, Matthew T.C., Park, Jin Sung, Kim, Jinhyun, Brickley, Stephen G., Chadderton, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083038/
https://www.ncbi.nlm.nih.gov/pubmed/30044974
http://dx.doi.org/10.1016/j.celrep.2018.06.076

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