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Blocking Ca(2+) Channel β(3) Subunit Reverses Diabetes

Voltage-gated Ca(2+) channels (Ca(v)) are essential for pancreatic beta cell function as they mediate Ca(2+) influx, which leads to insulin exocytosis. The β3 subunit of Ca(v) (Ca(v)β(3)) has been suggested to regulate cytosolic Ca(2+) ([Ca(2+)](i)) oscillation frequency and insulin secretion under...

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Detalles Bibliográficos
Autores principales:	Lee, Kayoung, Kim, Jaeyoon, Köhler, Martin, Yu, Jia, Shi, Yue, Yang, Shao-Nian, Ryu, Sung Ho, Berggren, Per-Olof
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083041/ https://www.ncbi.nlm.nih.gov/pubmed/30044988 http://dx.doi.org/10.1016/j.celrep.2018.06.086

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