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Structural Implications of Genotypic Variations in HIV-1 Integrase From Diverse Subtypes

Human immunodeficiency virus type 1 (HIV-1) integrase (IN) integrates viral DNA into the host genome using its 3′-end processing and strand-transfer activities. Due to the importance of HIV-1 IN, it is targeted by the newest class of approved drugs known as integrase strand transfer inhibitors (INST...

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Detalles Bibliográficos
Autores principales:	Rogers, Leonard, Obasa, Adetayo E., Jacobs, Graeme B., Sarafianos, Stefan G., Sönnerborg, Anders, Neogi, Ujjwal, Singh, Kamalendra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083056/ https://www.ncbi.nlm.nih.gov/pubmed/30116231 http://dx.doi.org/10.3389/fmicb.2018.01754

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