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Effects of aspirin on risks of vascular events and cancer according to bodyweight and dose: analysis of individual patient data from randomised trials
BACKGROUND: A one-dose-fits-all approach to use of aspirin has yielded only modest benefits in long-term prevention of cardiovascular events, possibly due to underdosing in patients of large body size and excess dosing in patients of small body size, which might also affect other outcomes. METHODS:...
Autores principales: | Rothwell, Peter M, Cook, Nancy R, Gaziano, J Michael, Price, Jacqueline F, Belch, Jill F F, Roncaglioni, Maria Carla, Morimoto, Takeshi, Mehta, Ziyah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083400/ https://www.ncbi.nlm.nih.gov/pubmed/30017552 http://dx.doi.org/10.1016/S0140-6736(18)31133-4 |
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