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Bacterial Cytological Profiling Reveals the Mechanism of Action of Anticancer Metal Complexes

[Image: see text] Target identification and mechanistic studies of cytotoxic agents are challenging processes that are both time-consuming and costly. Here we describe an approach to mechanism of action studies for potential anticancer compounds by utilizing the simple prokaryotic system, E. coli, a...

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Detalles Bibliográficos
Autores principales:	Sun, Yang, Heidary, David K., Zhang, Zhihui, Richards, Christopher I., Glazer, Edith C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2018
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083414/ https://www.ncbi.nlm.nih.gov/pubmed/29865789 http://dx.doi.org/10.1021/acs.molpharmaceut.8b00407

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