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Atypical presentation of a cushion sign-positive stomach gastrointestinal stromal tumor with cystic formation: A case report

Gastrointestinal stromal tumors (GIST) typically appear as solid masses, and cystic formation is uncommon. Most stomach GISTs with cystic formation progress outside the gastric wall and are frequently misdiagnosed as epigastric cystic tumors derived from pancreas or liver. An asymptomatic 72-year-ol...

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Autores principales: Okagawa, Yutaka, Sumiyoshi, Tetsuya, Ihara, Hideyuki, Oiwa, Shutaro, Tokuchi, Kaho, Yoshida, Masahiro, Fujii, Ryoji, Minagawa, Takeyoshi, Morita, Kohtaro, Hirayama, Michiaki, Kondo, Hitoshi, Oyamada, Yumiko, Kawarada, Yo, Kitashiro, Shuji, Okushiba, Shunichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083422/
https://www.ncbi.nlm.nih.gov/pubmed/30101015
http://dx.doi.org/10.3892/mco.2018.1639
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author Okagawa, Yutaka
Sumiyoshi, Tetsuya
Ihara, Hideyuki
Oiwa, Shutaro
Tokuchi, Kaho
Yoshida, Masahiro
Fujii, Ryoji
Minagawa, Takeyoshi
Morita, Kohtaro
Hirayama, Michiaki
Kondo, Hitoshi
Oyamada, Yumiko
Kawarada, Yo
Kitashiro, Shuji
Okushiba, Shunichi
author_facet Okagawa, Yutaka
Sumiyoshi, Tetsuya
Ihara, Hideyuki
Oiwa, Shutaro
Tokuchi, Kaho
Yoshida, Masahiro
Fujii, Ryoji
Minagawa, Takeyoshi
Morita, Kohtaro
Hirayama, Michiaki
Kondo, Hitoshi
Oyamada, Yumiko
Kawarada, Yo
Kitashiro, Shuji
Okushiba, Shunichi
author_sort Okagawa, Yutaka
collection PubMed
description Gastrointestinal stromal tumors (GIST) typically appear as solid masses, and cystic formation is uncommon. Most stomach GISTs with cystic formation progress outside the gastric wall and are frequently misdiagnosed as epigastric cystic tumors derived from pancreas or liver. An asymptomatic 72-year-old male underwent esophagogastroduodenoscopy, which revealed a submucosal tumor (SMT), approximately 50 mm in diameter, at the anterior wall of the gastric angle. The SMT was very soft with positive cushion sign. Endoscopic ultrasonography and contrast-enhanced computed tomography revealed that the SMT was a cystic tumor with solid component. Laparoscopic and endoscopic cooperative surgery were performed to remove the tumor. Histopathological analysis revealed that the tumor was a GIST with cystic formation. To the best of our knowledge, this the first documented case of a cushion sign-positive stomach GIST with cystic formation, which had mainly developed inside the stomach. This case suggests that we should keep in mind the possibility of cystic formation of GIST when the tumor has a solid component, even if it appears as a cushion sign-positive SMT.
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spelling pubmed-60834222018-08-10 Atypical presentation of a cushion sign-positive stomach gastrointestinal stromal tumor with cystic formation: A case report Okagawa, Yutaka Sumiyoshi, Tetsuya Ihara, Hideyuki Oiwa, Shutaro Tokuchi, Kaho Yoshida, Masahiro Fujii, Ryoji Minagawa, Takeyoshi Morita, Kohtaro Hirayama, Michiaki Kondo, Hitoshi Oyamada, Yumiko Kawarada, Yo Kitashiro, Shuji Okushiba, Shunichi Mol Clin Oncol Articles Gastrointestinal stromal tumors (GIST) typically appear as solid masses, and cystic formation is uncommon. Most stomach GISTs with cystic formation progress outside the gastric wall and are frequently misdiagnosed as epigastric cystic tumors derived from pancreas or liver. An asymptomatic 72-year-old male underwent esophagogastroduodenoscopy, which revealed a submucosal tumor (SMT), approximately 50 mm in diameter, at the anterior wall of the gastric angle. The SMT was very soft with positive cushion sign. Endoscopic ultrasonography and contrast-enhanced computed tomography revealed that the SMT was a cystic tumor with solid component. Laparoscopic and endoscopic cooperative surgery were performed to remove the tumor. Histopathological analysis revealed that the tumor was a GIST with cystic formation. To the best of our knowledge, this the first documented case of a cushion sign-positive stomach GIST with cystic formation, which had mainly developed inside the stomach. This case suggests that we should keep in mind the possibility of cystic formation of GIST when the tumor has a solid component, even if it appears as a cushion sign-positive SMT. D.A. Spandidos 2018-08 2018-05-25 /pmc/articles/PMC6083422/ /pubmed/30101015 http://dx.doi.org/10.3892/mco.2018.1639 Text en Copyright: © Okagawa et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Okagawa, Yutaka
Sumiyoshi, Tetsuya
Ihara, Hideyuki
Oiwa, Shutaro
Tokuchi, Kaho
Yoshida, Masahiro
Fujii, Ryoji
Minagawa, Takeyoshi
Morita, Kohtaro
Hirayama, Michiaki
Kondo, Hitoshi
Oyamada, Yumiko
Kawarada, Yo
Kitashiro, Shuji
Okushiba, Shunichi
Atypical presentation of a cushion sign-positive stomach gastrointestinal stromal tumor with cystic formation: A case report
title Atypical presentation of a cushion sign-positive stomach gastrointestinal stromal tumor with cystic formation: A case report
title_full Atypical presentation of a cushion sign-positive stomach gastrointestinal stromal tumor with cystic formation: A case report
title_fullStr Atypical presentation of a cushion sign-positive stomach gastrointestinal stromal tumor with cystic formation: A case report
title_full_unstemmed Atypical presentation of a cushion sign-positive stomach gastrointestinal stromal tumor with cystic formation: A case report
title_short Atypical presentation of a cushion sign-positive stomach gastrointestinal stromal tumor with cystic formation: A case report
title_sort atypical presentation of a cushion sign-positive stomach gastrointestinal stromal tumor with cystic formation: a case report
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083422/
https://www.ncbi.nlm.nih.gov/pubmed/30101015
http://dx.doi.org/10.3892/mco.2018.1639
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