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Inverse agonism of retinoic acid receptors directs epiblast cells into the paraxial mesoderm lineage
We have investigated the differentiation of paraxial mesoderm from mouse embryonic stem cells utilizing a Tbx6-EYFP/Brachyury (T)-Ckerry dual reporter system. Differentiation from the mouse ESC state directly into mesoderm via Wnt pathway activation was low, but augmented by treatment with AGN193109...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083448/ https://www.ncbi.nlm.nih.gov/pubmed/29807258 http://dx.doi.org/10.1016/j.scr.2018.05.016 |