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Prospects of Noncoding RNAs in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a global health problem and one of the most common malignant tumors. Recent studies have shown that noncoding RNAs (ncRNAs) contribute to the pathogenesis of hepatocellular carcinoma (HCC). These RNAs may be involved in a variety of pathological processes such as ce...

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Detalles Bibliográficos
Autores principales: Zhou, Huaixiang, Xu, Qiuran, Ni, Chao, Ye, Song, Xu, Xiaowu, Hu, Xiaoge, Jiang, Jiahong, Hong, Yeting, Huang, Dongsheng, Yang, Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083484/
https://www.ncbi.nlm.nih.gov/pubmed/30148169
http://dx.doi.org/10.1155/2018/6579436
Descripción
Sumario:Hepatocellular carcinoma (HCC) is a global health problem and one of the most common malignant tumors. Recent studies have shown that noncoding RNAs (ncRNAs) contribute to the pathogenesis of hepatocellular carcinoma (HCC). These RNAs may be involved in a variety of pathological processes such as cell proliferation, apoptosis, angiogenesis, invasion, and metastasis. In addition, abnormal expression of ncRNAs in HCC may provide potential prognostic or diagnostic biomarkers. This review provides an overview of the role and potential applications of ncRNAs, miRNAs, lncRNAs, circRNAs, and snoRNAs in liver cancer.