The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss

The rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a...

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Detalles Bibliográficos
Autores principales: Ruban, Aruchuna, Ashrafian, Hutan, Teare, Julian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083488/
https://www.ncbi.nlm.nih.gov/pubmed/30147720
http://dx.doi.org/10.1155/2018/7823182
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author Ruban, Aruchuna
Ashrafian, Hutan
Teare, Julian P.
author_facet Ruban, Aruchuna
Ashrafian, Hutan
Teare, Julian P.
author_sort Ruban, Aruchuna
collection PubMed
description The rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a device placed endoscopically in the duodenum, which is designed to mimic the effects of gastric bypass surgery with the aim of inducing weight loss and improving glycaemic control. This review outlines the current clinical evidence of the device, its efficacy, potential mechanisms of action, and utility in clinical practice.
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spelling pubmed-60834882018-08-26 The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss Ruban, Aruchuna Ashrafian, Hutan Teare, Julian P. Gastroenterol Res Pract Review Article The rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a device placed endoscopically in the duodenum, which is designed to mimic the effects of gastric bypass surgery with the aim of inducing weight loss and improving glycaemic control. This review outlines the current clinical evidence of the device, its efficacy, potential mechanisms of action, and utility in clinical practice. Hindawi 2018-07-26 /pmc/articles/PMC6083488/ /pubmed/30147720 http://dx.doi.org/10.1155/2018/7823182 Text en Copyright © 2018 Aruchuna Ruban et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ruban, Aruchuna
Ashrafian, Hutan
Teare, Julian P.
The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
title The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
title_full The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
title_fullStr The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
title_full_unstemmed The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
title_short The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
title_sort endobarrier: duodenal-jejunal bypass liner for diabetes and weight loss
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083488/
https://www.ncbi.nlm.nih.gov/pubmed/30147720
http://dx.doi.org/10.1155/2018/7823182
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