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LC-MS based sphingolipidomic study on A549 human lung adenocarcinoma cell line and its taxol-resistant strain

BACKGROUND: Resistance to chemotherapy drugs (e.g. taxol) has been a major obstacle in successful cancer treatment. In A549 human lung adenocarcinoma, acquired resistance to the first-line chemotherapy taxol has been a critical problem in clinics. Sphingolipid (SPL) controls various aspects of cell...

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Detalles Bibliográficos
Autores principales:	Huang, Hao, Tong, Tian-Tian, Yau, Lee-Fong, Chen, Cheng-Yu, Mi, Jia-Ning, Wang, Jing-Rong, Jiang, Zhi-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083515/ https://www.ncbi.nlm.nih.gov/pubmed/30089463 http://dx.doi.org/10.1186/s12885-018-4714-x

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