Cargando…

Dose-Dependent Antifibrotic Effect of Chrysin on Regression of Liver Fibrosis: The Role in Extracellular Matrix Remodeling

Liver fibrosis represents an overaccumulation of extracellular matrix (ECM). This study was designed to investigate the effect of chrysin on established ECM overproduction in carbon tetrachloride (CCl(4)) mouse liver fibrosis. Experimental fibrosis was induced by intraperitoneal injection of 2 mL/kg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Balta, Cornel, Ciceu, Alina, Herman, Hildegard, Rosu, Marcel, Boldura, Oana Maria, Hermenean, Anca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083810/ https://www.ncbi.nlm.nih.gov/pubmed/30108459 http://dx.doi.org/10.1177/1559325818789835

Ejemplares similares

Flucytosine and Amphotericin B Coadministration Induces Dose-Related Renal Injury
por: Folk, Alexandra, et al.
Publicado: (2017)

Phytochemical Profiling and Anti-Fibrotic Activities of the Gemmotherapy Bud Extract of Corylus avellana in a Model of Liver Fibrosis on Diabetic Mice
por: Balta, Cornel, et al.
Publicado: (2023)

Complexation with Random Methyl-β-Cyclodextrin and (2-Hidroxypropyl)-β-Cyclodextrin Enhances In Vivo Anti-Fibrotic and Anti-Inflammatory Effects of Chrysin via the Inhibition of NF-κB and TGF-β1/Smad Signaling Pathways and Modulation of Hepatic Pro/Anti-Fibrotic miRNA
por: Ciceu, Alina, et al.
Publicado: (2021)

Evaluation of Hepatotoxicity with Treatment Doses of Flucytosine and Amphotericin B for Invasive Fungal Infections
por: Folk, Alexandra, et al.
Publicado: (2016)

Complexation with Random Methyl-β-Cyclodextrin and (2-Hydroxypropyl)-β-Cyclodextrin Promotes Chrysin Effect and Potential for Liver Fibrosis Therapy
por: Ignat, Simona-Rebeca, et al.
Publicado: (2020)

Oral Administration of Vitamin D3 Prevents Corneal Damage in a Knock-Out Mouse Model of Sjögren’s Syndrome
por: Trotta, Maria Consiglia, et al.
Publicado: (2023)

Galectin 1—A Key Player between Tissue Repair and Fibrosis
por: Hermenean, Anca, et al.
Publicado: (2022)

Nano Selenium—Enriched Probiotics as Functional Food Products against Cadmium Liver Toxicity
por: Vicas, Simona Ioana, et al.
Publicado: (2021)

Cyclodextrin Complexation Improves the Solubility and Caco-2 Permeability of Chrysin
por: Fenyvesi, Ferenc, et al.
Publicado: (2020)

Chitosan-Graphene Oxide 3D scaffolds as Promising Tools for Bone Regeneration in Critical-Size Mouse Calvarial Defects
por: Hermenean, Anca, et al.
Publicado: (2017)

Antioxidant and Anti-Inflammatory Properties of a Thuja occidentalis Mother Tincture for the Treatment of Ulcerative Colitis
por: Stan, Miruna Silvia, et al.
Publicado: (2019)

Enhancement of Silymarin Anti-fibrotic Effects by Complexation With Hydroxypropyl (HPBCD) and Randomly Methylated (RAMEB) β-Cyclodextrins in a Mouse Model of Liver Fibrosis
por: Gharbia, Sami, et al.
Publicado: (2018)

H(2)O(2)-PLA-(Alg)(2)Ca Hydrogel Enriched in Matrigel(®) Promotes Diabetic Wound Healing
por: Bîrcă, Alexandra Cătălina, et al.
Publicado: (2023)

Biocompatibility and Antimicrobial Profile of Acid Usnic-Loaded Electrospun Recycled Polyethylene Terephthalate (PET)—Magnetite Nanofibers
por: Stoica (Oprea), Alexandra Elena, et al.
Publicado: (2023)

The morphological changes of the colonic goblet cells and mucin profile in oncohematological patients under Epirubicin-based chemotherapy
por: Cotoraci, Coralia Adina, et al.
Publicado: (2020)

Berberis vulgaris extract/β-cyclodextrin complex increases protection of hepatic cells via suppression of apoptosis and lipogenesis pathways
por: Ivan, Alexandra, et al.
Publicado: (2017)

Natural Antioxidants in Anemia Treatment
por: Cotoraci, Coralia, et al.
Publicado: (2021)

Graphene–Oxide Porous Biopolymer Hybrids Enhance In Vitro Osteogenic Differentiation and Promote Ectopic Osteogenesis In Vivo
por: Șelaru, Aida, et al.
Publicado: (2022)

Adipose-Derived Stem Cells (ADSCs) Supplemented with Hepatocyte Growth Factor (HGF) Attenuate Hepatic Stellate Cell Activation and Liver Fibrosis by Inhibiting the TGF-β/Smad Signaling Pathway in Chemical-Induced Liver Fibrosis Associated with Diabetes
por: Gharbia, Sami, et al.
Publicado: (2022)

Serum markers of the extracellular matrix remodeling reflect antifibrotic therapy in bile-duct ligated rats
por: Schierwagen, Robert, et al.
Publicado: (2013)

Electrospun Polyethylene Terephthalate Nanofibers Loaded with Silver Nanoparticles: Novel Approach in Anti-Infective Therapy
por: Grumezescu, Alexandru Mihai, et al.
Publicado: (2019)

The Anti-Leukemic Activity of Natural Compounds
por: Cotoraci, Coralia, et al.
Publicado: (2021)

Comprehensive Appraisal of Graphene–Oxide Ratio in Porous Biopolymer Hybrids Targeting Bone-Tissue Regeneration
por: Vlasceanu, George Mihail, et al.
Publicado: (2020)

Qualifying Osteogenic Potency Assay Metrics for Human Multipotent Stromal Cells: TGF-β2 a Telling Eligible Biomarker
por: Ofiteru, Augustin M., et al.
Publicado: (2020)

Thuja occidentalis L. (Cupressaceae): Ethnobotany, Phytochemistry and Biological Activity
por: Caruntu, Sonia, et al.
Publicado: (2020)

Recent Advancements in Antifibrotic Therapies for Regression of Liver Fibrosis
por: Jangra, Anshika, et al.
Publicado: (2022)

Utilization of Rosmarinic and Ascorbic Acids for Maturation Culture Media in Order to Increase Sow Oocyte Quality Prior to IVF
por: Boldura, Oana-Maria, et al.
Publicado: (2021)

The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome
por: Trotta, Maria Consiglia, et al.
Publicado: (2019)

Extracellular matrix and Hippo signaling as therapeutic targets of antifibrotic compounds for uterine fibroids
por: Islam, Md Soriful, et al.
Publicado: (2021)

Fingolimod and Diabetic Retinopathy: A Drug Repurposing Study
por: Gesualdo, Carlo, et al.
Publicado: (2021)

Aronia melanocarpa Ameliorates Adrenal Cytoarchitecture Against the Hexavalent Chromium-Induced Injury
por: Savici, Jelena, et al.
Publicado: (2020)

A novel experimental approach to evaluate guided bone regeneration (GBR) in the rat femur using a 3D-printed CAD/CAM zirconia space-maintaining barrier
por: Petre, Alexandru, et al.
Publicado: (2020)

Hepatoprotective activity of chrysin is mediated through TNF-α in chemically-induced acute liver damage: An in vivo study and molecular modeling
por: Hermenean, Anca, et al.
Publicado: (2017)

Sex and Age-Related Differences in Neuroinflammation and Apoptosis in Balb/c Mice Retina Involve Resolvin D1
por: Trotta, Maria Consiglia, et al.
Publicado: (2021)

Silk ProteinsEnriched Nanocomposite Hydrogels Based on Modified MMT Clay and Poly(2-hydroxyethyl methacrylate-co-2-acrylamido-2-methylpropane Sulfonic Acid) Display Favorable Properties for Soft Tissue Engineering
por: Șerban, Mirela Violeta, et al.
Publicado: (2022)

Bacterial Cellulose-Modified Polyhydroxyalkanoates Scaffolds Promotes Bone Formation in Critical Size Calvarial Defects in Mice
por: Codreanu, Ada, et al.
Publicado: (2020)

Interaction of Chrysin and Its Main Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide with Serum Albumin
por: Mohos, Violetta, et al.
Publicado: (2018)

Extracellular matrix remodelling in COPD
por: Karakioulaki, Meropi, et al.
Publicado: (2020)

Effects of Dietary Inclusion of Bilberry and Walnut Leaves Powder on the Digestive Performances and Health of Tetra SL Laying Hens
por: Popescu, Roua Gabriela, et al.
Publicado: (2020)

Extracellular Matrix Remodeling Factors as Markers of Carotid Artery Atherosclerosis
por: Sapa-Wojciechowska, Agnieszka, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_bltc55h0ajq2fpbdog7nkv9iqi