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Bone matrix development in steroid-induced osteoporosis is associated with a consistently reduced fibrillar stiffness linked to altered bone mineral quality
Glucocorticoid-induced osteoporosis (GIOP) is a major secondary form of osteoporosis, with the fracture risk significantly elevated – at similar levels of bone mineral density – in patients taking glucocorticoids compared with non-users. The adverse bone structural changes at multiple hierarchical l...
Autores principales: | Xi, L., De Falco, P., Barbieri, E., Karunaratne, A., Bentley, L., Esapa, C.T., Terrill, N.J., Brown, S.D.M., Cox, R.D., Davis, G.R., Pugno, N.M., Thakker, R.V., Gupta, H.S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084282/ https://www.ncbi.nlm.nih.gov/pubmed/29902593 http://dx.doi.org/10.1016/j.actbio.2018.05.053 |
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