RNA sequencing reveals upregulation of a transcriptomic program associated with stemness in metastatic prostate cancer cells selected for taxane resistance

Patients with metastatic castration-resistant prostate cancer (mCRPC) develop resistance to conventional therapies including docetaxel (DTX). Identifying molecular pathways underlying DTX resistance is critical for developing novel combinatorial therapies to prevent or reverse this resistance. To id...

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Detalles Bibliográficos
Autores principales: Cajigas-Du Ross, Christina K., Martinez, Shannalee R., Woods-Burnham, Leanne, Durán, Alfonso M., Roy, Sourav, Basu, Anamika, Ramirez, Joshua A., Ortiz-Hernández, Greisha L., Ríos-Colón, Leslimar, Chirshev, Evgeny, Sanchez-Hernandez, Evelyn S., Soto, Ubaldo, Greco, Celine, Boucheix, Claude, Chen, Xin, Unternaehrer, Juli, Wang, Charles, Casiano, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084384/
https://www.ncbi.nlm.nih.gov/pubmed/30100995
http://dx.doi.org/10.18632/oncotarget.25744

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