Doxorubicin-induced elevated oxidative stress and neurochemical alterations in brain and cognitive decline: protection by MESNA and insights into mechanisms of chemotherapy-induced cognitive impairment (“chemobrain”)

Chemotherapy-induced cognitive impairment (CICI) is now widely recognized as a real and too common complication of cancer chemotherapy experienced by an ever-growing number of cancer survivors. Previously, we reported that doxorubicin (Dox), a prototypical reactive oxygen species (ROS)-producing ant...

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Detalles Bibliográficos
Autores principales: Keeney, Jeriel T. R., Ren, Xiaojia, Warrier, Govind, Noel, Teresa, Powell, David K., Brelsfoard, Jennifer M., Sultana, Rukhsana, Saatman, Kathryn E., Clair, Daret K. St., Butterfield, D. Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084398/
https://www.ncbi.nlm.nih.gov/pubmed/30100992
http://dx.doi.org/10.18632/oncotarget.25718

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