Cargando…
Pyrrolo[3,2-c]pyridine derivatives with potential inhibitory effect against FMS kinase: in vitro biological studies
A series of eighteen pyrrolo[3,2-c]pyridine derivatives were tested for inhibitory effect against FMS kinase. Compounds 1e and 1r were the most potent among all the other tested analogues (IC(50) = 60 nM and 30 nM, respectively). They were 1.6 and 3.2 times, respectively, more potent than our lead c...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084503/ https://www.ncbi.nlm.nih.gov/pubmed/30070930 http://dx.doi.org/10.1080/14756366.2018.1491563 |