Post-transplant lymphoproliferative disorder presenting on post-transplant Day 35 as a pulmonary parenchymal infiltrate—a case report

Post-transplant lymphoproliferative disorder (PTLD), a rare but serious complication of solid organ transplantation, is classified into early-onset and late-onset subtypes. Early-onset PTLD occurs a median of 4–11 months after lung transplantation. It rarely presents in the first 2 months post-trans...

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Autores principales: Lewis, Andrew J, Jagadeesh, Deepa, Mukhopadhyay, Sanjay, Budev, Marie, Mehta, Atul C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084571/
https://www.ncbi.nlm.nih.gov/pubmed/30109030
http://dx.doi.org/10.1093/omcr/omy035
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author Lewis, Andrew J
Jagadeesh, Deepa
Mukhopadhyay, Sanjay
Budev, Marie
Mehta, Atul C
author_facet Lewis, Andrew J
Jagadeesh, Deepa
Mukhopadhyay, Sanjay
Budev, Marie
Mehta, Atul C
author_sort Lewis, Andrew J
collection PubMed
description Post-transplant lymphoproliferative disorder (PTLD), a rare but serious complication of solid organ transplantation, is classified into early-onset and late-onset subtypes. Early-onset PTLD occurs a median of 4–11 months after lung transplantation. It rarely presents in the first 2 months post-transplant. Early-onset PTLD usually presents as a solitary pulmonary nodule. We present a unique case of early-onset PTLD that was diagnosed on post-operative Day 35 and presented as a pulmonary parenchymal infiltrate. This case is also exceptional in that the patient had a significant clinical response to only a single dose of rituximab.
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spelling pubmed-60845712018-08-14 Post-transplant lymphoproliferative disorder presenting on post-transplant Day 35 as a pulmonary parenchymal infiltrate—a case report Lewis, Andrew J Jagadeesh, Deepa Mukhopadhyay, Sanjay Budev, Marie Mehta, Atul C Oxf Med Case Reports Case Report Post-transplant lymphoproliferative disorder (PTLD), a rare but serious complication of solid organ transplantation, is classified into early-onset and late-onset subtypes. Early-onset PTLD occurs a median of 4–11 months after lung transplantation. It rarely presents in the first 2 months post-transplant. Early-onset PTLD usually presents as a solitary pulmonary nodule. We present a unique case of early-onset PTLD that was diagnosed on post-operative Day 35 and presented as a pulmonary parenchymal infiltrate. This case is also exceptional in that the patient had a significant clinical response to only a single dose of rituximab. Oxford University Press 2018-08-09 /pmc/articles/PMC6084571/ /pubmed/30109030 http://dx.doi.org/10.1093/omcr/omy035 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Lewis, Andrew J
Jagadeesh, Deepa
Mukhopadhyay, Sanjay
Budev, Marie
Mehta, Atul C
Post-transplant lymphoproliferative disorder presenting on post-transplant Day 35 as a pulmonary parenchymal infiltrate—a case report
title Post-transplant lymphoproliferative disorder presenting on post-transplant Day 35 as a pulmonary parenchymal infiltrate—a case report
title_full Post-transplant lymphoproliferative disorder presenting on post-transplant Day 35 as a pulmonary parenchymal infiltrate—a case report
title_fullStr Post-transplant lymphoproliferative disorder presenting on post-transplant Day 35 as a pulmonary parenchymal infiltrate—a case report
title_full_unstemmed Post-transplant lymphoproliferative disorder presenting on post-transplant Day 35 as a pulmonary parenchymal infiltrate—a case report
title_short Post-transplant lymphoproliferative disorder presenting on post-transplant Day 35 as a pulmonary parenchymal infiltrate—a case report
title_sort post-transplant lymphoproliferative disorder presenting on post-transplant day 35 as a pulmonary parenchymal infiltrate—a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084571/
https://www.ncbi.nlm.nih.gov/pubmed/30109030
http://dx.doi.org/10.1093/omcr/omy035
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